For U.S. Residents Only

Glossary

Alpha-1 blockers
Medications used to treat the symptoms of benign prostatic hyperplasia by relaxing the smooth muscles of the prostate and bladder neck

Benign
Not cancerous; a benign growth does not invade surrounding tissue or spread to other parts of the body

Benign Prostatic Hyperplasia (BPH)
Abnormal growth of the prostate not due to cancer or infection

Bladder
The organ that stores urine

Cancer
An abnormal, uncontrolled growth in any tissue or organ in the body that can spread to surrounding or distant organs

Digital rectal exam
Test in which the doctor inserts a gloved finger into the anus to feel the prostate for any unusual features such as hardness, bumps or swelling

Dihydrotestosterone (DHT)
A hormone derived from testosterone and thought to be involved in prostate enlargement

Ejaculation
The sudden release of semen through the penis during sexual climax

Enlarged prostate
Common name for benign prostatic hyperplasia

Gland
An organ that makes and secretes substances used by the body

Hyperplasia
Benign enlargement or growth

Impotence
Inability to sustain an erection sufficient for intercourse

Kidney
Either of a pair of organs in the dorsal region of the vertebrate abdominal cavity, functioning to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes, which are then excreted as urine

Prostate cancer
The presence of cancerous cells in the prostate

Prostate-specific Antigen (PSA)
A protein in semen produced by the prostate gland and measured in the blood in patients with BPH or prostate cancer

Prostatic (adj)
Related to the prostate

Retrograde ejaculation (dry climax)
A condition in which semen enters the bladder during ejaculation and is later flushed out during urination

Semen
The fluid, containing sperm, which exits the penis during ejaculation

Testes
Male reproductive glands where sperm are produced. Also the main source of testosterone in males

Testosterone
The most potent male hormone

Urethra
The tube that carries urine and semen out through the penis

Urinary flow test
Measure of the amount of urine voided per second

Urinary tract infection
Infection of an element of the urinary system, including the urethra, the bladder, the ureters or the kidneys

Watchful waiting
Period of time after diagnosis of a disease during which no active treatments are pursued; rather, the condition is monitored at frequent intervals


Indication
UROXATRAL® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.

Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.

UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure.

Before taking UROXATRAL, tell your doctor if you have kidney problems.

Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.

BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.

The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.

Please see UROXATRAL patient information.