For U.S. Residents Only
UROXATRAL® is an alpha1-blocker for the treatment of the signs and symptoms of BPH.

Glossary

Alpha-1 Blocker

A medication used to treat the symptoms of benign prostatic hyperplasia (BPH) by relaxing the smooth muscles of the prostate and bladder neck.

Benign

Not cancerous; a benign growth does not invade surrounding tissue or spread to other parts of the body.

Benign Prostatic Hyperplasia (BPH)

Abnormal growth of the prostate not due to cancer or infection.

Bladder

The organ that stores urine.

Cancer

An abnormal, uncontrolled growth in any tissue or organ in the body that can spread to surrounding or distant organs.

Digital Rectal Exam (DRE)

Test in which the doctor inserts a gloved finger into the anus to feel the prostate for any unusual features such as hardness, bumps or swelling.

Dihydrotestosterone (DHT)

A hormone derived from testosterone and thought to be involved in prostate enlargement.

Ejaculation

The sudden release of semen through the penis during sexual climax.

Enlarged Prostate

Common name for benign prostatic hyperplasia (BPH).

Gland

An organ that makes and secretes substances used by the body.

Hormone

A chemical produced by a gland in the body that regulates various biological functions.

Hyperplasia

Benign enlargement or growth.

Impotence

Inability to sustain an erection sufficient for intercourse.

Kidney

Either of a pair of organs in the that, among other things, help to maintain proper water and electrolyte balances in the body and filter the blood of waste, which is then excreted as urine.

Prostate Cancer

The presence of cancerous cells in the prostate.

Prostate Gland

A walnut- or chestnut-shaped organ, the prostate is a gland that surrounds the beginning of the urethra and produces a milky fluid that provides nutrient to the sperm and is discharged into the urethra at the time of semen emission.

Prostate-Specific Antigen (PSA)

A protein in semen produced by the prostate gland and found in larger-than-normal quantities in the blood of patients with prostate cancer.

Prostatic (adj)

Related to the prostate.

Retrograde Ejaculation (dry climax)

A condition in which semen enters the bladder during ejaculation and is later flushed out during urination.

Semen

A fluid that contains sperm and exits the penis during ejaculation.

Testes

Male reproductive glands where sperm are produced. Also the main source of testosterone in men.

Testosterone

The most potent male hormone.

Urethra

The tube that carries urine and semen out through the penis.

Urinary Flow Test

A test that measures the amount of urine exiting the urethra.

Urinary Tract infection

Infection of a part of the urinary system, including the urethra, the bladder or the kidneys.

Watchful Waiting

Period of time after diagnosis of a disease during which no active treatments are pursued; rather, the condition is monitored at frequent intervals.

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Important Safety Information

Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.

UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.

If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.

Before taking UROXATRAL, tell your doctor if you have kidney problems.

Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.

BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.

The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.

Please see full prescribing information.

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